Bis-peg25-nhs ester
Bis-PEG25-NHS ester
CAS: 2221948-96-3
Molecular Formula: C62H112N2O33
Bis-peg25-nhs ester - Names and Identifiers
| Name | Bis-PEG25-NHS ester |
| Synonyms | Bis-PEG25-NHS ester Bis-peg25-nhs ester Bis-dPEG25-NHS ester |
| CAS | 2221948-96-3 |
Bis-peg25-nhs ester - Physico-chemical Properties
| Molecular Formula | C62H112N2O33 |
| Molar Mass | 1413.55 |
| Storage Condition | 2-8°C，避光，干燥，密封 |
| In vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Bis-peg25-nhs ester - Reference Information
| biological activity | Bis-PEG25-NHS ester is a PROTAC connection bridge, belonging to PEG and Alkyl/ether. Bis-PEG25-NHS ester can be used to synthesize a series of PROTAC molecules. Bis-PEG25-NHS ester is a degradable (cleavable) ADC link bridge for the synthesis of antibody drug conjugates (ADCs). |
| target | PEGs Alkyl/ether Cleavable |
| in vitro study | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. |
Last Update：2024-04-09 20:52:54
